I removed the grip safety of my 7.63 Mauser made in the 70's.
Most of the safety mechanism which is under the grip on the left side has to be left by my method, which leaves the manual safety functional though running backwards, ie up vs down. The gaps in the rear of the grip panels were filled with a walnut wood and I had my gunsmith checker to match. In the closeup photo you can see that we didn't get the wood as well matched as we thought we had, it's darker.
If I were considering it again I wouldn't do it even though it's mechanically perfect, and it wouldn't be difficult to return to original condition by just buying a replacement grip safety and removing the walnut from the gaps.
However due to collector value I think I'd buy a mismatched shooter instead, an old beat up P-08 with rust pitting and worn off bluing shoots exactly the same as a pristine collector gun, so it makes no sense to semi-permanently modify one.